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FDA: Seizure Drug Zonisamide Can Cause Metabolic Acidosis, Damage Kidneys & Bones

According to the FDA, side effects of the anti-seizure drug Zonisamide may lead to the development of Metabolic Acidosis, a blood PH imbalance that can cause hyperventilation, cardiac arrhythmias, stupor, and non-specific symptoms such as anorexia and fatigue, and may also have adverse effects on bones, kidneys, and normal childhood growth.

The FDA warned health care professionals of these potential side effects after reviewing updated clinical data on adults with epilepsy who were treated for partial seizures. Accordingly, the FDA recommends that, both before and during treatment with Zonisamide, health care professionals measure serum levels of bicarbonate, even if symptoms are not present.

If Metabolic Acidosis has developed in the patient, the health care professional should either reduce dosage of Zonisamide or discontinue it altogether (after tapering the dosage). However, if the patient must continue using Zonisamide even after developing Metabolic Acidosis, the FDA advises health care professionals to consider alkali treatment.

If you think you may have been injured from using Zonisamide, please contact Carr & Carr. The defective drug lawyers at Carr & Carr Attorneys at Law can help you receive compensation for your injuries. To receive a complimentary consultation with a lawyer, contact Carr & Carr Attorneys or call 1-877-392-4878. We have offices located in Oklahoma City, Tulsa or Northwest Arkansas locations.

Posted by Lesa H.

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